Objective: To review the current knowledge of CAD/CAM in dentistry and its development in the mentioned field. Sources: An electronic search was conducted across Ovid Medline, complemented by manual search across individual databases, such as Cochrane, Medline and ISI Web of Science databases and Google Scholar for literature analysis on the mentioned topic. The studies were reviewed thoroughly. This paper summarizes the current scientific and clinical opinions through a brief overview regarding the preferred way of utilizing CAD/CAM in dentistry. Conclusions: The importance of CAD/CAM systems has seen a dramatic development in the number of products and procedures over last decades, with a concomitant rise in publications on the topic. Literature suggests that using this technology permits carrying out dental treatments feasibly particularly for fixed dental appliances. Based on the previous findings, it is concluded that in office CAD/CAM technique appears to be the most common technique currently available, which is rapid, easy and keeps time. CAD/CAM systems are variable; therefore, using the right system with a logical approach for treating patients are quite mandatory.

Background and Aim: Chairside Computer-Aided Design/Computer-Aided manufacturing (CAD/CAM) systems have become considerably more accurate, reliable, efficient, fast, and prevalent since 1985 when CEREC was introduced. The inceptive restorative material option for chairside CAD/CAM restorations was limited to ceramic blocks. Today, restorative material options have been multiplied and include metal alloys, ceramics, oxide ceramics, resins, and resin-matrix ceramics (RMC). This study aimed at making an overview of chairside CAD/CAM system materials and classifications. Materials and Methods: An electronic search of the literature was carried out mainly through PubMed, ScienceDirect, Cochrane Library, and Google Scholar. The search aimed at collecting all the relevant English articles from 1965 to 2020. Result: The analysis of the bond strength, fatigue resistance, flexural strength, elastic constants, microstructural characterization, accuracy, and clinical success of the materials showed variable outcomes. The marginal adaptation of resin ceramics has been reported to be comparable to that of lithium disilicate. It has been reported that the chairside CAD/CAM system using intraoral scanning is at least as accurate as the conventional method. Conclusion: Chairside CAD/CAM restorations are fast, reliable, predictable, effective, patient-friendly, and cost-effective treatment options. Design software and intraoral scanners have made the treatment procedure simple. Chairside individualization of dental restorations could help improve patient satisfaction. However, considering the limited long-term clinical data, future studies need to address the longterm clinical performance of chairside CAD/CAM materials.